Specialists in Custom synthesis of challenging and complex Organic compounds
Syndoz is always keen to take up the challenges in ‘hard to do’ syntheses of building blocks, reference compounds of intermediates, Glucuronides metabolites and stable isotope (2D, 13C, 15N) labelled standards synthesis, complex multi-step synthesis of lead compounds, impurities, metabolites and degradation products. We are committed to timeliness in delivery, dependability in quality of products and efficiency in process development.
After consultation with the client and an initial evaluation, our scientists will develop a detailed synthesis proposal including a scientific literature search and review, starting materials and reagent availability and costs, and a detail of costs for each synthesis step and cost of required analytical identification tests like NMR, LC-MS, HPLC etc. At each step we will try to incorporate eco-friendly and green chemistry techniques.
Our team of Ph.D. organic chemists have expertise in many varieties of chemistry and we can meet your synthesis needs in the following areas:
Scale up Custom Synthesis
Since initial research laboratory batch size is not suitable for preparing grams of target product, our staff will adopt a synthesis that best suits our clients’ expectations
Metabolite and Glucuronide synthesis
Syndoz offer quick and efficient synthesis of Glucuronides and other metabolites of Active molecules. Compounds obtained are isolated, identified and delivered according to your requirements.
Process Optimization
From an existing scalable process or patent development, Our Scientists can develop new and proprietary synthesis schemes and execute using current technology. We offer design of experiments, real-time reaction profiles and total process development.
Syndoz offers two modes of operation:
– Custom Synthesis (Projects with known Synthesis scheme)
The Custom Synthesis involves Synthesis of compounds for which synthetic procedures are available either (i) the methods have already been described in Scientific literature or (ii) our customer provides literature, methods, or their own synthesis route(s), describing all steps in detail. In Some cases, a similar synthesis of related chemical entity may also be applicable to this approach.
If you have any questions or for additional information, please contact us or send an email to info@syndoz.com
– R&D Based Synthesis (FTE Projects)
This type of work involves full time involvement of our scientists working on the project at the bench. Generally, Such FTE (Full Time Equivalent) projects involve more complex or longer-term projects. Most of the times, compounds being synthesized have not been described in any literature. The proposals for Synthesis of such compounds may need to be designed before being executed. Once a project is completed, a research agreement will be drawn up. All projects are conducted under strict confidentiality.
If you have any Custom synthesis inquiry or require additional information, please contact us or send an email to info@syndoz.com
